The NAIMAN global objective is further decomposed into the following sub-objectives to face the previous requirements:

• Self-adjusting regulation system for trustworthy and sustainable manufacturing systems: to define a set of design principles of the regulation system for governing manufacturing systems to operate trustworthy and sustainably, as well as to respond quickly and flexibly to endogenous (e.g., product quality, machine failure, energy policy) and exogenous (e.g., customer demand, COVID-19, environmental regulations) changes.
• Human overseeing the regulation system: to create mechanisms that enable humans to be in-the-loop (HITL), on-the-loop (HOTL), or in-command (HIC) in the design, supervision, and decision-making processes of regulated manufacturing systems.
• Prototypical deployments: to demonstrate the applicability of the proposed contributions in various Industry of the Future platforms.